There’s a lot of wireframing tips floating around online but they rarely focus on just web applications. It’s cool to see that kind of web focus over on Intercom’s design blog. Pay special attention to point three which focuses on speed and exploration:
If you can’t produce concepts quickly, then you’re working at the wrong fidelity. If your wire-framing serves only to deliver a grayscale version of what you’ve already decided you’re building then you’re wasting everyones time.