From Mac/iOS app developer Bjango’s blog, a solid primer on why sub-pixel antialiasing – still fairly common on Chrome and the PC world – is on its way out. This part really surprised me:
WebKit on OS X disables sub-pixel antialiasing when animating, often resulting in a visual glitch when it starts and stops, unless standard antialiasing is set using CSS. OS X disables sub-pixel antialiasing when using CoreAnimation’s layer backed views.
Now I know why some of my CSS3 font animations can run a bit off; turns out it was for good reason.