Paravel founder Trent Walton on the transition to building responsive web sites properly:
I believe this starts with a shift in perception. Whether massive or minute, this shift usually involves letting go of a lot of assumptions that center around desktop-centric browsing.
I found myself nodding a lot to Trent’s post. There’s no one simple solution for implementing responsive web design, but trying to just take an existing desktop workflow (e.g. fixed width psd comps, jamming a few CSS media queries on existing work) won’t do it justice.